- Mitochondria-influencing compounds
- Composition based on Bruce Ames' research
- 200 mg acetyl-L-carnitine and 200 mg R-α-lipoic acid (from R-α-lipoic acid sodium salt)
- Ingredients in a stable formulation
- No additives or fillers
- Laboratory tested for heavy metals
- Contents: 60 capsules/servings
PURE Macarena Capsules – A special blend
Each of your cells contains mitochondria, tiny power plants that manage energy production. Certain factors such as aging, intense exercise, and environmental influences can affect efficiency.
PURE Macarena by Edubily combines two essential substances: acetyl-L-carnitine and R-α-lipoic acid, which are being studied in research related to mitochondrial function.
Bruce Ames' discovery on cell health
Over 20 years ago, renowned molecular biologist Bruce Ames and his team investigated the effects of acetyl-L-carnitine and α-lipoic acid on aging rats, as these two substances were already part of research on energy metabolism and antioxidant properties. The goal was to test the influence of the supplements in an animal model.
Ames humorously summarized the results in a press release at the time:
"With the two drugs together, these old rats stood up and danced the Macarena," Ames said. ...
(source)
Combination therapy with acetyl-L-carnitine and α-lipoic acid targets mitochondrial function:
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Acetyl-L-carnitine It is described in research in connection with carnitine acetyltransferase. It protects this enzyme and helps it perform its function efficiently.
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α-lipoic acid is described as having antioxidant properties in the mitochondria.
(1)(2)
The researchers described the results in rats as remarkable.
"We significantly reduced the decline in overall activity typical of old rats to the level of a young to middle-aged rat, between 7 and 10 months of age," Hagen said.
(source)
In a subsequent study, the research team focused more on the cognitive performanceHere, too, older rats were fed a combination of acetyl-L-carnitine and α-lipoic acid. (3).
(1) Liu, J., Killilea, D.W., and Ames, B.N. (2002) Age-associated Mitochondrial Oxidative Decay: Improvement of Carnitine Acetyltransferase Substrate Binding Affinity and Activity in Brain by Feeding Old Rats Acetyl-L-Carnitine and/or R-α-Lipoic Acid. Proc. Natl. Acad. Sci. U.S.A. 99, 1876-1881
(2) Hagen, T.M., Liu, J., Lykkesfeldt, J., Wehr, C.M., Ingersoll, R.T., Vinarsky, V., Bartholomew, J.C., and Ames, B.N. (2002) Feeding Acetyl-L-Carnitine and Lipoic Acid to Old Rats Significantly Improves Metabolic Function while Decreasing Oxidative Stress. Proc. Natl. Acad. Sci. U.S.A. 99, 1870-1875.
(3) Liu, J., Head, E., Gharib, A.M., Yuan, W., Ingersoll, R.T. Hagen, T.M., Cotman, C.W., and Ames, B.N.(2002) Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and/or R-α-Lipoic Acid. Proc. Natl. Acad. Sci. U.S.A. 99, 2356-2361.
PURE Macarena – High-quality ingredients in the PURE range
PURE Macarena is part of Edubily’s PURE range – that means no additives, no hidden ingredients.
The formula contains an optimally bioavailable form of acetyl-L-carnitine and stabilized R-α-lipoic acid sodium salt. Both substances were carefully selected and combined in a balanced formula.
Nutritional values
| Contents | per serving (= 1 capsule) |
|---|---|
| R-α-lipoic acid (from R-α-lipoic acid sodium salt) | 200 mg |
| L-acetylcarnitine | 200 mg |
Ingredients
R-α-lipoic acid sodium salt, L-acetylcarnitine hydrochloride, hydroxypropylmethylcellulose (capsule shell).
Recommended intake: Take 1 serving (= 1 capsule) daily 1-2 hours before a meal without chewing and with sufficient water.
Notes: Do not exceed the recommended daily intake. This product is not a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Store in a cool, dry place away from light.

Quality & safety at the highest standard
Edubily attaches great importance to developing and manufacturing products on a scientifically sound basis. Their production is carried out by experienced partners in Germany and Austria, who are regularly inspected without notice and are certified according to IFS Food and HACCP. This means that Edubily meets strict hygiene and safety requirements. Furthermore, all products are retested in independent laboratories for factors such as heavy metals, nutrient content, and possible contaminants. Edubily's goal is not to simply offer any nutritional supplements, but rather safe and effective ones that promote health and well-being through well-thought-out formulations and continuous development. This way, fitness athletes and health-conscious individuals can be assured of receiving a high-quality and responsibly designed product.